Year: 2023
Type: preprint
Study design: Case Report
Abstract: Pediatric cutaneous T-cell lymphoma with γδ immunophenotype is extremely rare. Only a few cases of γδ T-cell neoplasm have been reported in the literature and therefore little is known whether γδ T-cell neoplasms in children are distinct from their adult counterparts with respect to the clinicopathological presentation, behavior and prognosis. In this study, we demonstrate three unique cases with increased γδ T-cells in malignant and non-malignant skin conditions of children. All cases showed an indolent clinical course. Full integration of clinical presentation, morphology, immunophenotype, and genetics supports the correct diagnosis and guides the treatment.
Institutions: Children's National, MedStar Georgetown University Hospital
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4387100226