Work

Hepatitis C Treatment in People With HIV: Potential to Eliminate Disease and Disparity

Year: 2023

Type: article

Study design: Observational Study

Abstract: Access to direct acting antivirals (DAAs) may be associated with reductions in hepatitis C virus (HCV) viremia prevalence among people with human immunodeficiency virus (PWH). Among 3755 PWH, estimated HCV viremia prevalence decreased by 94.0% from 36% (95% confidence interval [CI], 27%-46%) in 2009 (pre-DAA era) to 2% (95% CI, 0%-4%) in 2021 (DAA era). Male sex, black race, and older age were associated with HCV viremia in 2009 but not in 2021. Injection drug use remained associated with HCV viremia in 2009 and 2021. Targeted interventions are needed to meet the HCV care needs of PWH who use drugs.

Source: The Journal of Infectious Diseases

DOI: 10.1093/infdis/jiad433

Authors: Oluwaseun Falade-Nwulia, Catherine R Lesko, Anthony T Fojo, Jeanne C Keruly, Richard D Moore, Catherine G Sutcliffe, Shruti H Mehta, Geetanjali Chander, David L Thomas, Mark Sulkowski

Institutions: Johns Hopkins University, Johns Hopkins Medicine, University of Washington

Language: English

Topic: Hepatitis C virus research

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Reduced inequalities

Open Access status: green

Funders: National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, National Institute of Mental Health, National Institute on Drug Abuse, National Institute on Minority Health and Health Disparities

Awards: G2456272280, G2509593258, G2516619799, Optimizing outcomes at the intersection of HIV and mental health: Prediction, precision medicine, and population health, Elimination of HCV and related liver disease among HIV-infected and -uninfected people who inject drugs, G607165691, G9000074434, G9000121099, G9000203738, G9000240911, Ending the HIV Epidemic in Rural America (EHE-RA): Local Interventions, Co-Epidemics, and Social Determinants

OpenAlex ID: W4387324643

FWCI: 0.986

Cites: 11

Cited by: 7

Related to: 10