Work

Stem-Cell Aging and Pathways to Precancer Evolution

Year: 2023

Type: review

Abstract: Stem cells can renew themselves without differentiating. Aging, inflammation, and environmental exposures may drive phenotypic changes in tissue stem cells that cause them to become cancer stem cells.

Source: New England Journal of Medicine

DOI: 10.1056/nejmra2304431

Authors: Catriona H.M. Jamieson, Irving L. Weissman

Institutions: University of California San Diego, Stanford Medicine, Institute for Stem Cell Biology and Regenerative Medicine

Language: English

Topic: Cancer Cells and Metastasis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Aeronautics and Space Administration, California Institute for Regenerative Medicine, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Award: Stem Cell Biology, Cancer Stem Cell Biology, and Cancer Immunotherapy

OpenAlex ID: W4387324713

FWCI: 1.224

Cites: 76

Cited by: 39

Related to: 10