Work

Seed Becoming Soil: A New Paradigm of the Ewing Sarcoma Tumor Microenvironment

Year: 2023

Type: article

Abstract: Cells in the tumor microenvironment, including cancer-associated fibroblasts (CAF), contribute to tumor growth and immune evasion. A recent study of Ewing sarcoma identified "CAF-like" tumor cells that mimic the protumorigenic features of CAFs. These findings highlight the role of cell plasticity in tumor growth. See related article by Wrenn et al., p. 5140.

Source: Clinical Cancer Research

DOI: 10.1158/1078-0432.ccr-23-2259

Authors: Christopher Kuo, James F. Amatruda

Institutions: University of Southern California, Children's Hospital Los Angeles

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green