Work

143P Genomic characterization and outcomes of patients with primary sclerosing cholangitis-related cholangiocarcinoma

Year: 2023

Type: article

Abstract: Cholangiocarcinoma (CCA) is the leading cause of death in patients (pts) with primary sclerosing cholangitis (PSC). PSC-related CCA is rare, and there has been no clinical analysis of survival outcomes following surgery, radiation therapy (RT), or systemic therapy. Risk of autoimmune disease flare with immunotherapy also has yet to be reported. We aim to characterize treatment responses and clinical outcomes in relation to tumor mutational profiles.

Source: ESMO Open

DOI: 10.1016/j.esmoop.2023.101993