Controlling the Assembly of Cellulose‐Based Oligosaccharides through Sequence Modifications
Year: 2023
Type: article
Abstract: Peptides and nucleic acids with programmable sequences are widely explored for the production of tunable, self‐assembling functional materials. Herein we demonstrate that the primary sequence of oligosaccharides can be designed to access materials with tunable shapes and properties. Synthetic cellulose‐based oligomers were assembled into 2D or 3D rod‐like crystallites. Sequence modifications within the oligosaccharide core influenced the molecular packing and led to the formation of square‐like assemblies based on the rare cellulose IVII allomorph. In contrast, modifications at the termini generated elongated aggregates with tunable surfaces, resulting in self‐healing supramolecular hydrogels.
Source: Angewandte Chemie
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $5,250
Awards: G2121614283, G292453335, 3D electron crystallography of carbohydrates: structural diversity and radiation sensitivity, G443779809, G4484000448, Glycan foldamers: designing oligosaccharides to build three-dimensional architectures, G6461442376, SFB 1449: Dynamische Hydrogele an Biogrenzflächen, G7556184027, Synthetischer Ansatz zur kontrollierten Herstellung von Materialien aus Kohlenhydraten, von NANO-Technologie zur BULK-Produktion
OpenAlex ID: W4387570912