P‐BB‐32 | Effect of COVID‐19 Precautions on Donor Adverse Events (DAE) in the Apheresis Donor Population at a Hospital‐Based Donor Center
Year: 2023
Type: article
Study design: Observational Study
Abstract: The COVID-19 pandemic caused by the SARS-CoV-2 virus changed the daily operations of donor centers across the nation. Masking and limiting donor refreshment (food and beverages) while donating became widespread precautions to stop the spread of the SARS-CoV-2 infection within the donor center. Donor refreshment during the prolonged apheresis collection process mitigates fluid loss and lowers the risk of donor adverse events (DAE). The DAE rate of the platelet and plasma apheresis donor population before and after COVID-19 precautions were compared to assess for any change in donor safety risk from these precautions. A 2-year pre-precaution period from 2018 to 2019 where donor refreshment was routine during apheresis collection and a 2-year COVID-19 precaution period from 2021 to 2022 where masking was required, and no donor refreshment was allowed during apheresis collection were selected. For each period, total collections, total DAE, total unique donors, and total unique donors with a DAE were obtained. For the study DAE is defined as only citrate reactions and vasovagal reactions. DAE rates were compared between periods using a chi-square test with Yates' continuity correction with a statistical significance cut-off of p < .05. During the pre-precaution period, 11,159 total collections from 1495 unique donors experienced 20 DAE from 17 unique donors resulting in 1.16% of unique donors having a DAE episode. During the precaution period, 13,147 total collections from 1830 unique donors experienced 33 DAE from 30 unique donors, resulting in a 1.64% of unique donors having a DAE episode (see Table 1). Pre-precaution DAE versus precaution DAE rates. DAE, donor adverse events.
Source: Transfusion
Authors: A. Anderson, K. Duffy, J. Juskewitch, C. van Buskirk
Institution: Mayo Clinic
Language: English
Subfield: Management of Technology and Innovation
Domain: Social Sciences
Open Access status: bronze
OpenAlex ID: W4387577459