Work

Author response: Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein

Year: 2023

Type: peer-review

Abstract: Functional studies on CFTR anion channels harboring combinations of catalytic site mutations in the active ATPase site reveal the true stability of the prehydrolytic open-pore state as well as nucleotide-binding domain interface features that are unique to human CFTR.

Source: eLife

DOI: 10.7554/elife.90736.sa2

Authors: Márton A Simon, Iordan Iordanov, Andras Szollosi, László Csanády

Institutions: Semmelweis University, Hungarian Research Network

Language: English

Topic: Cystic Fibrosis Research Advances

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $2,500

Funders: Nemzeti Kutatási Fejlesztési és Innovációs Hivatal, Innovációs és Technológiai Minisztérium, Nemzeti Kutatási, Fejlesztési és Innovaciós Alap, National Research, Development and Innovation Office