DNA damage induced by CDK4 and CDK6 blockade triggers anti-tumor immune responses through cGAS-STING pathway
Work
Year: 2023
Type: article
Abstract: CDK4/6 are important regulators of cell cycle and their inhibitors have been approved as anti-cancer drugs. Here, we report a STING-dependent anti-tumor immune mechanism responsible for tumor suppress... more
Source: Communications Biology
Institutions Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Qilu Hospital of Shandong University, Soochow University, First Affiliated Hospital of Soochow University +6 more
Cites: 46
Cited by: 19
Related to: 10
FWCI: 4.473
Citation percentile (by year/subfield): 99.99
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Sustainable Development Goal Good health and well-being
Open Access status: gold
APC paid (est): $2,890
Funders National Natural Science Foundation of China, National Natural Science Foundation of China, Natural Science Foundation of Jiangsu Province, Chinese Academy of Medical Sciences
Grant IDS 81874067, 81802870, BK20211554, 2021-1-I2M-047