Work

Changes of gray matter volumes of subcortical regions across the lifespan: a Human Connectome Project study

Year: 2023

Type: article

Abstract: We report mixed effects of age on subcortical grey matter volume (GMV) during lifespan ( n = 2458, 5-90 yr old, 1113 male, 1345 female). Striatal and cerebellar GMVs decreased linearly with age, more steeply in males. In contrast, GMVs of the amygdala, pallidum, thalamus, ventral diencephalon, and brainstem changed in a quadratic fashion, increasing first and decreasing afterward, with males peaking earlier than females in all regions but the brainstem where they peaked at nearly the same time.

Source: Journal of Neurophysiology

DOI: 10.1152/jn.00283.2023

Authors: Peka Christova, Apostolos P. Georgopoulos

Institutions: University of Minnesota, Minneapolis VA Health Care System, Minneapolis VA Medical Center

Language: English

Topic: Functional Brain Connectivity Studies

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green