Work

Site‐specifically radiolabeled nanobodies for imaging blood‐brain barrier penetration and targeting in the brain

Year: 2023

Type: review

Abstract: Nanobodies (Nbs) hold significant potential in molecular imaging due to their unique characteristics. However, there are challenges to overcome when it comes to brain imaging. To address these obstacles, collaborative efforts and interdisciplinary research are needed. This article aims to raise awareness and encourage collaboration among researchers from various fields to find solutions for effective brain imaging using Nbs. By fostering cooperation and knowledge sharing, we can make progress in overcoming the existing limitations and pave the way for improved molecular imaging techniques in the future.

Source: Journal of Labelled Compounds and Radiopharmaceuticals

DOI: 10.1002/jlcr.4069

Authors: Yingbo Li, Junfeng Wang

Institutions: Peking University, State Key Laboratory of Natural and Biomimetic Drugs, Harvard University, Gordon Center for Medical Imaging, Massachusetts General Hospital

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: bronze

Funders: National Institutes of Health, National Institute on Aging

Award: Development of PET imaging probes for metabolic glutamate receptor 3 (mGLuR3)