Work

TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells

Year: 2023

Type: article

Source: Nature Aging

DOI: 10.1038/s43587-023-00505-y

Authors: Tingting Hong, Jia Li, Lei Guo, Maryn Cavalier, Tianlu Wang, Yaling Dou, Aaron DeLaFuente, Shaohai Fang, Anna Guzman, Katherina Wohlan, Chiraag Kapadia, Carina Rosas, Yaling Yang, C. Cameron Yin, Shaoying Li, M. James You, Xiaodong Cheng, Margaret A. Goodell, Yubin Zhou, Yun Huang

Institutions: Texas A&M University, First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Baylor College of Medicine, The University of Texas MD Anderson Cancer Center

Language: English

Topic: Epigenetics and DNA Methylation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, Welch Foundation, Cancer Prevention and Research Institute of Texas, Leukemia and Lymphoma Society, National Institute on Aging, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: NanoOptogenetic immunotherapy for B cell lymphoma, G2448744268, G2518563489, G2779659605, G35063665, Regulation of Hematopoietic Progenitors by de novo DNA Methylation, G4464524862, Selective targeting of a Rho GTPase mutant for peripheral T cell lymphoma treatment, G5131083043, G540484151, G5749691131, G6222068007, REGULATION OF HEMATOPOIETIC PROGENITORS BY DE NOVO DNA METHYLATION, G6661208262, Tunable epigenetic remodeling to modulate CAR T-cell based immunotherapy, G6891797479, G7378569363, G8162689062, G9000068781, DNMT3A in Development of Hematologic Malignancies, Mutational cooperativity in TET2-associated hematological malignancies., Mutual reinforcement between somatic mutations and transcription factors in clonal hematopoiesis, Modifiable Drivers of Expansion and Malignant Transformation from Clonal Hematopoiesis, Molecular Regulation of Stem Cell Aging, Baylor College of Medicine Cancer Center - Cancer Center Support Grant, Epigenetic regulation in cardiac development

OpenAlex ID: W4387955539

FWCI: 3.545

Cites: 57

Cited by: 41

Related to: 10