Work

Reviews of "Crossing Host Boundaries: The Evolutionary Drivers and Correlates of Viral Host Jumps"

Year: 2023

Type: peer-review

Abstract: This preprint concludes that human-to-animal viral transmission exceeds zoonotic transmission, based on phylogenetic analysis of genomic databases.However, reviewers caution that biases in available sequences may impact reconstructing transmission histories.They recommend the authors validate findings using Bayesian phylogenetics on subsets of data, account for gaps due to intermediate hosts, and clarify analysis limitations.Additionally, reviewers suggest breaking down transmission patterns by host taxa and route to provide more nuanced insights.Overall, they find the topic important but advise strengthening methodology and interpretation to address potential biases in genomic databases.

DOI: 10.1162/2e3983f5.1e90e54a

Authors: Cara Brook, Brian Foley

Institutions: University of Chicago, Los Alamos National Laboratory, Massachusetts Institute of Technology

Language: English

Topic: Zoonotic diseases and public health

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

Open Access status: gold

OpenAlex ID: W4388015919

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