Calcium carbonate urolithiasis in a diabetic pet rabbit fed with high dietary calcium- Causal effect study and its surgical management
Year: 2023
Type: article
Study design: Case Report
Abstract: A nine years old New Zealand White female diabetic rabbit (blood glucose level~300 mg/dL) was presented to the Out Patient Department (OPD) of Veterinary Clinical Complex, Kolkata, India with a history of chronic weight loss along with inappetence, polyuria, haematuria from last 10 days.Feeding history revealed that the animal was maintained with a mixed diet that is rich in calcium (Ca).Manual examination revealed moderate pain near the caudal abdominal region, and a hard mass was palpated at the level of the urinary bladder.Straight lateral radiograph of the abdomen showed the presence of radiodense cystolith.Hence, cystotomy was done, and the rabbit recovered uneventfully.The analysis of the stone revealed calcium carbonate as a major content.The present article describes successful surgical management of urolith in a rabbit and confers ample evidence that high calcium diet, peculiar Ca metabolism along with higher intake of carbohydrates that increase the risk of diabetes, may setup urolithiasis.The present study also emphasises the fact that diminished Na+-K+-ATPase activity in diabetes can play a pivotal role in the pathogenesis of peripheral vascular and neural complications leading to the development of bladder dysfunction, diminished urine flow in diabetic rabbits resulting in nidus formation and thereby further accumulation of calcium salts in and around nidus leads to the formation of urolithiasis.
Source: Indian Journal of Animal Health
Authors: C. M. Tarif, S. Roy, P. Mukherjee, S. S. Kesh
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4388232655