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Dynein‐Powered Cell Locomotion Guides Metastasis of Breast Cancer (Adv. Sci. 31/2023)

Year: 2023

Type: article

Abstract: Dynein-Powered Cell Locomotion Human breast adenocarcinoma MDA-MB-231 cell demonstrates metastatic-like adhesion, spreading and migration on the biomimetic collagen matrix. In article number 2302229 by Amir Sheikhi, Denis Tsygankov, Erdem D. Tabdanov, and co-workers, non-canonical breast cancer cells' locomotion mechanism has been identified, based on the motricity of the dynein motors that generate and transmit the mechanical forces between F-actin and microtubules cytoskeletons. Dynein-powered cell locomotion facilitates cell motility in the absence of the conventional myosin-driven cell migration.

Source: Advanced Science

DOI: 10.1002/advs.202370215

Authors: Yerbol Tagay, Sina Kheirabadi, Zaman Ataie, Rakesh K. Singh, Olivia Prince, Ashley Nguyen, Alexander S. Zhovmer, Xuefei Ma, Amir Sheikhi, Denis Tsygankov, Erdem D. Tabdanov

Language: English

Topic: Cellular Mechanics and Interactions

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,720

OpenAlex ID: W4388342177

FWCI:

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