Work

Figure S5 from PRMT5 Inhibitors Regulate DNA Damage Repair Pathways in Cancer Cells and Improve Response to PARP Inhibition and Chemotherapies

Year: 2023

Type: other

Abstract: PRT543 inhibits growth of PARP inhibitor resistant ovarian and breast cancer models in vitro and in vivo.

DOI: 10.1158/2767-9764.24512221

Authors: Jack Carter, Michael Hulse, Monisha Sivakumar, Jessica Burtell, Venkat Thodima, Min Wang, Anjana Agarwal, Komali Vykuntam, Jacob Spruance, Neha Bhagwat, Joseph Rager, Bruce Ruggeri, Peggy Scherle, Koichi Ito

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4388422966

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