Work

Development of a new class of potent and highly selective G protein-coupled receptor kinase 5 inhibitors and structural insight from crystal structures of inhibitor complexes

Year: 2023

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2023.115931

Authors: Yueyi Chen, Amol Sonawane, Rajesh Manda, Ranjith Kumar Gadi, John J.G. Tesmer, Arun K. Ghosh

Institution: Purdue University West Lafayette

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Walther Cancer Foundation, Purdue University, National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute

Awards: Cancer Center Support Grant, Structure, function, and inhibition of G protein-coupled receptor kinases

OpenAlex ID: W4388563245

FWCI: 1.154

Cites: 52

Cited by: 13

Related to: 10