Work

Expansion of platform physiologically-based pharmacokinetic model for monoclonal antibodies towards different preclinical species: cats, sheep, and dogs

Year: 2023

Type: article

Source: Journal of Pharmacokinetics and Pharmacodynamics

DOI: 10.1007/s10928-023-09893-5

Authors: Hsien-Wei Huang, Shengjia Wu, Ekram A. Chowdhury, Dhaval K. Shah

Institution: University at Buffalo, State University of New York

Language: English

Topic: Monoclonal and Polyclonal Antibodies Research

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, Center for Protein Therapeutics, University at Buffalo

Awards: G1272326302, Translational Systems Pharmacokinetic Models of Novel Anticancer Biologics, G4473175299, G6857409683, Modulation of antigen pharmacokinetics with pH dependent antibody, Pharmacokinetic / Pharmacodynamic Optimization of ADC Therapy for Acute Myeloid Leukemia, Enhancement of ADC selectivity by inverse targeting: Mechanistic studies and optimization

OpenAlex ID: W4388568147

FWCI: 0.166

Cites: 59

Cited by: 1

Related to: 10