PB1467 Hospital-Acquired (HA) versus Post-Discharge (PD) Venous Thromboembolism (VTE) Similarities and Differences: Analysis of the Medical Inpatient Thrombosis and Hemostasis (MITH) Population
Year: 2023
Type: conference-abstract
Abstract: Aims: The aim of this study is to assess whether the highest risk patient populations are reflected in the randomized control trial data.Methods: A systemic review of literature was performed, using PubMed and The Cochrane Library databases.The articles included met the following criteria: prospective, randomized controlled studies with more than100 acute PE patients and were published after the year 2000.Each article was reviewed by two different members of our team.Data on demographics and comorbidities associated with disease severity was extracted for further analysis.Results: The literature search yielded 7473 articles.After duplicate removals and further screening, only 25 articles met our eligibility criteria (Figure 1).Mortalities per comorbidity was seldom included in any of the studies, and thus, presenting percent mortality per comorbidity was not feasible.The weighted averages for the comorbidities associated with disease severity are presented in Table 1.The most reported characteristics were age, sex, hypertension, diabetes, heart failure, history of VTE and malignancy.Coronary artery disease was reported in 3/25 studies.The percent weighted averages were higher for males (46.7%), patients with hypertension (38%) and hyperlipidemia (43%).The weighted average for Caucasians was 70%; thus only 30% of the population included was non-white.
Authors: M. Gergi, A. Sparks, K. Wilkinson, R. Thomas, N. Roetker, N. Smith, N. Zakai
Language: English
Subfield: Internal Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,250
OpenAlex ID: W4388601536