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Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models

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Year: 2023
Type: article
Source: Nature Methods
DOI: 10.1038/s41592-023-02082-9
Authors: Muyuan Chen, Michael F. Schmid, Wah Chiu
Institutions: SLAC National Accelerator Laboratory, Stanford Synchrotron Radiation Lightsource, Stanford University
Language: English

Topic: Advanced Electron Microscopy Techniques and Applications
Subfield: Structural Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: green

Funders: U.S. Department of Health and Human Services, Silicon Valley Community Foundation, National Institutes of Health, National Institute of Mental Health, National Institute of General Medical Sciences, SLAC National Accelerator Laboratory
Awards: G2380543539, G3115871832, Determining structure and organization of neurofilaments in situ using cryo- electron tomography, G4893461164, G6719595188, G6813909988, Mechanisms of CLC Transporters and Channels, G9000010735
OpenAlex ID: W4388728609
FWCI: 2.475
Cites: 29
Cited by: 28
Related to: 10
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