Work

Recent advances in 3D bioprinted cartilage-mimicking constructs for applications in tissue engineering

Year: 2023

Type: review

Abstract: Human cartilage tissue can be categorized into three types: hyaline cartilage, elastic cartilage and fibrocartilage. Each type of cartilage tissue possesses unique properties and functions, which presents a significant challenge for the regeneration and repair of damaged tissue. Bionics is a discipline in which humans study and imitate nature. A bionic strategy based on comprehensive knowledge of the anatomy and histology of human cartilage is expected to contribute to fundamental study of core elements of tissue repair. Moreover, as a novel tissue-engineered technology, 3D bioprinting has the distinctive advantage of the rapid and precise construction of targeted models. Thus, by selecting suitable materials, cells and cytokines, and by leveraging advanced printing technology and bionic concepts, it becomes possible to simultaneously realize multiple beneficial properties and achieve improved tissue repair. This article provides an overview of key elements involved in the combination of 3D bioprinting and bionic strategies, with a particular focus on recent advances in mimicking different types of cartilage tissue.

Source: Materials Today Bio

DOI: 10.1016/j.mtbio.2023.100870

Authors: Jian Zhou, Qi Li, Zhuang Tian, Qi Yao, Mingzhu Zhang

Institutions: Beijing Tongren Hospital, Capital Medical University, Beijing Shijitan Hospital

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $3,150

Funder: National Natural Science Foundation of China