Work

The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma

Year: 2023

Type: article

Abstract: In this issue, Pang and colleagues 1 identify the protease legumain as a potential immunotherapy target in glioblastoma that drives tumor-associated macrophages in response to hypoxia.

Source: Cell Reports Medicine

DOI: 10.1016/j.xcrm.2023.101293

Authors: Jonathan Mitchell, Bruno Colon, Defne Bayik, Justin D. Lathia

Institutions: University of Miami, Sylvester Comprehensive Cancer Center, Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland Clinic Research

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics (clinical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,460

Funder: National Institute of General Medical Sciences

Award: Medical Scientist Training Program

OpenAlex ID: W4388871119

FWCI: 0.83

Cites: 11

Cited by: 5

Related to: 10