Work

Development of immunoliposomes containing cytotoxic gold payloads against HER2-positive breast cancers

Year: 2023

Type: article

Abstract: 3 accumulates in the cells more than 3 and that the unencapsulated payload accumulates primarily in lysosomes, while targeted liposomal 3 localizes in mitochondria and ER, hinting at different possibilities for modes of action.

Source: RSC Medicinal Chemistry

DOI: 10.1039/d3md00334e

Authors: Afruja Ahad, Fatima Aftab, Alexa Michel, Jason S. Lewis, Maria Contel

Institutions: The Graduate Center, CUNY, Memorial Sloan Kettering Cancer Center, City University of New York, Brooklyn College

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: City University of New York, Memorial Sloan-Kettering Cancer Center, Tow Foundation, Weill Cornell Medical College, National Cancer Institute, National Institute of General Medical Sciences

Awards: Titanium-gold-based chemotherapeutics for prostate and kidney cancer, Cancer Center Support Grant, Annotating Cancer Biology through Non-Invasive Molecular Imaging, Platinum-Gold Compounds as Potential Chemo- and Targeted Agents for Ovarian Cancer, Biodegradable nanocarriers and antibodies as targeting delivery vehicles for cancer metallodrugs

OpenAlex ID: W4388876746

FWCI: 0.51

Cites: 58

Cited by: 8

Related to: 10