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Identification of LY3522348: A Highly Selective and Orally Efficacious Ketohexokinase Inhibitor

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Year: 2023
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c01410
Authors: Timothy B. Durham, Junliang Hao, Patrick Spinazze, Douglas R. Stack, James L. Toth, Steven Massey, Curren T. Mbofana, Richard D. Johnston, Jayana P. Lineswala, Aaron Wrobleski, Jose Miguel Mínguez, Carlos Perez, Daryl L. Smith, Jason Lamar, Rebecca Leon, Christopher Corkins, Jim Durbin, Frances Tung, Sherry Guo, Ryan J. Linder, Nathan Yumibe, Wei Wang, James MacKrell, Meghan Antonellis, Bethany Mascaro
Institutions: Eli Lilly (United States), Eli Lilly (Spain)
Language: English

Topic: Synthesis and biological activity
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: National Institute of General Medical Sciences
Award: ALS Efficiently Networking Advanced Beam Line Experiments (ALS-ENABLE)
OpenAlex ID: W4388898704
FWCI: 1.021
Cites: 27
Cited by: 10
Related to: 10
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