Work

Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations

Year: 2023

Type: article

Abstract: We retrospectively study twenty-nine surgical cases of aggressive vertebral hemangiomas (AVHs) with neurological deficits and extradural compression to determine the optimal surgical treatment strategy for AVHs at a single institution. Patients with AVHs with neurological deficits who underwent partial tumor resection plus decompression with or without vertebroplasty (VP), and radiotherapy between 2010 and 2021 were included in this study. Clinical characteristics, surgical outcomes, and follow-up data of the patients were reviewed retrospectively. Twenty-nine AVH cases with neurological deficits and spinal instability were included in this study and treated surgically. The mean operation time of patients with decompression surgery plus VP was 215.9 (120–265 min) shorter than that of decompression surgery without VP 240.2 (120–320 min). Intraoperative blood loss was 273.3 (100–550 mL) in the decompression plus VP group and 635.3 (200–1600 mL) in the decompression group. In addition, a significant reduction in blood loss was observed in the decompression plus VP group compared to the decompression group (p = 0.016). All patients experienced immediate pain relief and improvement in their neurological symptoms, and the visual analogue scale (VAS) pain score decreased from 7.4 (4–9) to 1.3 (0–3). Of twenty-nine patients in this study, only two showed signs of recurrence. Decompression plus VP achieve good tumor control and decrease surgical complication. Preoperative vascular embolization and VP can reduce intraoperative bleeding in the treatment of AVH surgery. Moreover, postoperative radiotherapy seems to be a good technique to prevent tumor recurrence.

Source: Journal of bone oncology

DOI: 10.1016/j.jbo.2023.100515