Work

Author Response: Baited reconstruction with 2D template matching for high-resolution structure determination in vitro and in vivo without template bias

Year: 2023

Type: peer-review

Abstract: 2D template matching enables a streamlined single-particle cryogenic electron microscopy workflow that can be used to discover new high-resolution structural features in molecules and complexes, such as bound ligands and drugs.

Source: eLife

DOI: 10.7554/elife.90486.3.sa4

Authors: Bronwyn A Lucas, Benjamin A Himes, Nikolaus Grigorieff

Institutions: University of California, Berkeley, University of Massachusetts Chan Medical School

Language: English

Topic: Advanced Electron Microscopy Techniques and Applications

Subfield: Structural Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W4389046394

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