Non-canonical pathway for Rb inactivation and external signaling coordinate cell-cycle entry without CDK4/6 activity
Work
Year: 2023
Type: article
Abstract: Cyclin-dependent kinases 4 and 6 (CDK4/6) are critical for initiating cell proliferation by inactivating the retinoblastoma (Rb) protein. However, mammalian cells can bypass CDK4/6 for Rb inactivatio... more
Source: Nature Communications
Authors Mimi Zhang, Sungsoo Kim, Hee Won Yang
Institution Columbia University
Cites: 62
Cited by: 20
Related to: 10
FWCI: 5.91
Citation percentile (by year/subfield): 100
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
APC paid (est): $4,808
Funders American Cancer Society, V Foundation for Cancer Research, Melanoma Research Foundation, National Institute of General Medical Sciences
Grant IDS RSG-22-101-01-CDP, V2023-017, , R01-GM145884