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Preliminary Results from a Phase 1 Dose Escalation Study of FHD-286, a Novel BRG1/BRM (SMARCA4/SMARCA2) Inhibitor, Administered As an Oral Monotherapy in Patients with Advanced Hematologic Malignancies

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Year: 2023
Type: conference-abstract
Source: Blood
DOI: 10.1182/blood-2023-178090
Authors: Courtney D. DiNardo, Michael R. Savona, Ashwin Kishtagari, Amir T. Fathi, Kapil N. Bhalla, Samuel Agresta, Sarah Reilly, Caroline Almon, Murphy Hentemann, Denice Hickman, Dillon Corrigan, Meghan Macaraeg, Jessica Piel, Kim Horrigan, Salah Nabhan, Paul Martin, Eytan M. Stein
Institutions: The University of Texas MD Anderson Cancer Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Massachusetts General Hospital, Foghorn Therapeutics (United States), Memorial Sloan Kettering Cancer Center
Language: English

Topic: Chromatin Remodeling and Cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W4389220735
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Cited by: 20
Related to: 10
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