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Author response: Glucagon-like peptide-1 receptor activation stimulates PKA-mediated phosphorylation of Raptor and this contributes to the weight loss effect of liraglutide

Year: 2023

Type: peer-review

Abstract: The ability of the therapeutic glucagon-like peptide-1 receptor agonist liraglutide to promote weight loss is partly dependent on signaling via PKA-dependent phosphorylation of the mTORC1 regulator protein Raptor.

Source: eLife

DOI: 10.7554/elife.80944.sa2

Authors: Thao DV Le, Dianxin Liu, Gai-Linn K Besing, Ritika Raghavan, Blair J Ellis, Ryan P Ceddia, Sheila Collins, Julio E Ayala

Institutions: Vanderbilt University, Vanderbilt University Medical Center

Language: English

Topic: Regulation of Appetite and Obesity

Subfield: Endocrine and Autonomic Systems

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500

Funders: Vanderbilt University, National Institutes of Health

Award: Promethion Core System

OpenAlex ID: W4389251566

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