Work

Tuning enantioselective drug adsorption in isoreticular homochiral metal–peptide frameworks through proximity pore interactions

Year: 2025

Type: article

Abstract: Homochiral MOFs with tunable pore sizes enable controlled adsorption of racemic drugs, achieving up to 76.1% enantiomeric excess for l -penicillamine through proximity-driven interactions.

Source: Journal of Materials Chemistry B

DOI: 10.1039/d5tb02047f

Authors: James Ho, Ankit K. Yadav, Andrzej Gładysiak, Andrew P. Carpenter, Anjali Verma, Matthew A. Cranswick, Adrian Henle, Mas A. Subramanian, Joe Baio, Kyriakos C. Stylianou

Institution: Oregon State University

Language: English

Topic: Metal-Organic Frameworks: Synthesis and Applications

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Science Foundation, Oregon State University, Business Oregon

Awards: G497139189, Nonlinear Surface Spectroscopic Investigations into the Molecular Mechanism Governing Cell Membrane Repair, NNCI: Northwest Nanotechnology Infrastructure (NNI)

OpenAlex ID: W4416288555

FWCI:

Cites: 44

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Related to: 10