ATM/ATR Phosphorylation of CtIP on Its Conserved Sae2-like Domain Is Required for Genotoxin-Induced DNA Resection but Dispensable for Animal Development
Work
Year: 2023
Type: article
Abstract: Homology-directed repair (HDR) of double-strand DNA breaks (DSBs) is dependent on enzymatic resection of DNA ends by the Mre11/Rad50/Nbs1 complex. DNA resection is triggered by the CtIP/Sae2 protein, ... more
Source: Cells
Institutions Columbia University, Cancer Genetics (United States), Columbia University Irving Medical Center
Cites: 48
Cited by:
Related to: 10
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Citation percentile (by year/subfield):
Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
APC paid (est): $2,382
Grant ID P30-CA013696