Work

ATAC-seq, primary human T cells overexpressing BATF3 v1

Year: 2023

Type: preprint

Abstract: This protocol describes methods for performing ATACseq on human HER2 targeted CAR T cells overexpressing BATF3 or GFP. Chromatin remodeling was assessed in acutely and chronically stimulated cells.

DOI: 10.17504/protocols.io.4r3l22pmql1y/v1

Authors: Sean R. McCutcheon, Adam M. Swartz, Michael C. Brown, Alejandro Barrera, Christian McRoberts Amador, Keith Siklenka, Lucas Humayun, Maria A. ter Weele, James M. Isaacs, Andrea R Daniel, Timothy E. Reddy, Andrew S. Allen, Smita K. Nair, Scott J. Antonia, Charles A. Gersbach

Institution: Duke University

Language: English

Topic: CAR-T cell therapy research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4389608197

Cites: 5

Cited by: 1

Related to: 10