Work

TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments

Year: 2023

Type: article

Source: Immunity

DOI: 10.1016/j.immuni.2023.11.010

Authors: Yuan-Li Tsai, Marcel Arias-Badia, Theresa A. Kadlecek, Yee May Lwin, Aahir Srinath, Neel H. Shah, Zhi-En Wang, Diane Barber, John Kuriyan, Lawrence Fong, Arthur Weiss

Institutions: University of California, San Francisco, Russell/Engleman Rheumatology Research Center, Columbia University, Howard Hughes Medical Institute, Vanderbilt University, UCSF Helen Diller Family Comprehensive Cancer Center

Language: English

Topic: Protein Tyrosine Phosphatases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Howard Hughes Medical Institute, Cancer Research Institute, Prostate Cancer Foundation, Damon Runyon Cancer Research Foundation, Emory University, National Institutes of Health, University of California, San Francisco, National Cancer Institute, National Institute of Allergy and Infectious Diseases

Awards: Molecular and Cellular Mechanisms in Cancer, Determinants of response to cancer immunotherapy, Defining the Unique Properties of the Distinct Signaling Machinery Used by the TCR

OpenAlex ID: W4389626420

FWCI: 2.549

Cites: 101

Cited by: 34

Related to: 10