Work

Application of SERS Nanoparticles for Imaging for Fast, Sensitive and Selective Cancer Screening: A Review

Year: 2023

Type: article

Abstract: Surface Enhanced Raman Spectroscopy (SERS) is a rapid, label-free, modular, non-destructive, and multiplexed imaging technique used in a number of applications for both elemental and biological analysis.Its flexible, sensitive, and adaptive nature makes SERS an excellent platform for cancer imaging.In the context of nanomedicine, SERS has shown tremendous utility.Several different nanoparticles have been used in SERS for cancer imaging, and includes the most widely studied gold nanoparticles, with silver nanoparticles, carbon-based nanoparticles, and metal oxide semiconductor nanoparticles gaining popularity in recent years.SERS nanoparticles can be tuned to suit nearly any application as the nanoparticle cores, surface coatings, and targeting moieties can be strategically designed for use in biological applications for in situ, in vivo, in vitro, and ex vivo analyses.Since SERS is an emerging cancer diagnostic technology, frequent reviews of the SERS nanoparticle schemes are necessary to inform the research community while ensuring the most cutting-edge SERS technologies continue to be developed.In this review, SERS nanoparticles used in the past five years for cancer imaging will be analyzed, with a focus on the type of nanoparticle as well as the type of cancer to which it is applied.

Source: Significances of Bioengineering & Biosciences

DOI: 10.31031/sbb.2023.06.000629

Author: Tahrima B Rouf

Institution: University of Oklahoma

Language: English

Topic: Gold and Silver Nanoparticles Synthesis and Applications

Subfield: Electronic, Optical and Magnetic Materials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Institutes of Health