Work

Tools for assembling the cell: Towards the era of cell structural bioinformatics

Year: 2023

Type: conference-paper

Abstract: Cells consist of large components, such as organelles, that recursively factor into smaller systems, such as condensates and protein complexes, forming a dynamic multi-scale structure of the cell. Recent technological innovations have paved the way for systematic interrogation of subcellular structures, yielding unprecedented insights into their roles and interactions. In this workshop, we discuss progress, challenges, and collaboration to marshal various computational approaches toward assembling an integrated structural map of the human cell.

Source: Pacific Symposium on Biocomputing (PSB)

DOI: 10.1142/9789811286421_0052

Authors: Mengzhou Hu, Xikun Zhang, Andrew Latham, Andrej Šali, Trey Ideker, Emma Lundberg

Institutions: University of California San Diego, Stanford University, University of California, San Francisco

Language: English

Topic: Bioinformatics and Genomic Networks

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funder: National Cancer Institute

Award: The Cancer Cell Map Initiative v2.0