Work

Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis

Year: 2023

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2023.116080

Authors: Xuetao Chen, Tingting Wu, Zhiyan Du, Wenjing Kang, Rujun Xu, Fanying Meng, Chihong Liu, Yali Chen, Qichao Bao, Jingkang Shen, Qidong You, Danyan Cao, Zhengyu Jiang, Xiaoke Guo

Institutions: China Pharmaceutical University, State Key Laboratory of Natural Medicine, Chinese Academy of Sciences, Shanghai Institute of Materia Medica

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4389974943

FWCI: 1.186

Cites: 77

Cited by: 16

Related to: 10