Work

FIGURE 4 from Immunologic Signatures of Peripheral Blood T Cells Reveal the Outcome of p53MVA Vaccine and Pembrolizumab Treatment in Patients with Advanced Ovarian Cancer

Year: 2023

Type: other

Abstract: Multiplex gene expression analysis of pretreatment PBMC samples identifies a set of genes of potential predictive value. mRNA expression levels of indicated genes that differentiate R (green bars) from NR (red bars) are shown for two pairs of representative patients (A). Expanded analysis of mRNA expression in additional pretreatment PBMC samples in R (n = 5) and NR (n = 12), plus normal healthy controls (C, n = 3; B), confirms the trend observed in A that is further quantified in unpaired two-tailed t test. *, P < 0.05.

DOI: 10.1158/2767-9764.24877837.v1

Authors: Ferdynand J. Kos, Paul Frankel, Mihaela Cristea, Melissa Eng, Raechelle Tinsley, Shannon Dempsey, Nora Ruel, Daphne Stewart, Thanh H. Dellinger, Don J. Diamond

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4389994480

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