Work

A Single-Nucleus Transcriptome-Wide Association Study Implicates Novel Genes in Depression Pathogenesis

Year: 2023

Type: article

Study design: Observational Study

Source: Biological Psychiatry

DOI: 10.1016/j.biopsych.2023.12.012

Authors: Lu Zeng, Masashi Fujita, Zongmei Gao, Charles C. White, Gilad S. Green, Naomi Habib, Vilas Menon, David A. Bennett, Patricia Boyle, Hans-Ulrich Klein, Philip L. De Jager

Institutions: Columbia University Irving Medical Center, Hebrew University of Jerusalem, Rush University Medical Center

Language: English

Topic: Genetic Associations and Epidemiology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute on Aging

Awards: Epidemiologic Study of Neural Reserve and Neurobiology of Aging, G2273097277, G3612828264, Pathway discovery, validation and compound identification for Alzheimer's disease, Risk Factors, Pathology, and Clinical Expressions of AD, Rush Alzheimer's Disease Core Center, Multi-omic network-directed proteoform discovery, dissection and functional validation to prioritize novel AD therapeutic targets, G6769186038, Deconstructing and modeling the single cell architecture of the Alzheimer brain, Alzheimer variants: Propagation of shared functional changes across cellular networks, Rush Alzheimer's Disease Research Center

OpenAlex ID: W4390052660

FWCI: 4.981

Cites: 69

Cited by: 30

Related to: 10