Work

Characterization and Prognostic Implications of Respirophasic Variation in Invasive Hemodynamic Measurements at Rest and With Exercise

Year: 2024

Type: article

Abstract: Pulmonary capillary wedge pressure (PCWP) is a key measure of left heart congestion used to establish or rule out the diagnosis of heart failure (HF). Diagnostic algorithms for HF with preserved ejection fraction (HFpEF) include or are validated based on rest and exercise PCWP measurements.1 However, previous studies have reached conflicting conclusions about whether PCWP measurements should be assessed at end-expiration (PCWPend-exp) or as a global mean across respiratory cycles (PCWPmean).2-4 In clinical practice heterogeneity in reporting mean vs.

Source: Journal of Cardiac Failure

DOI: 10.1016/j.cardfail.2023.12.009

Authors: Joseph Campain, Ilya Giverts, Mark W. Schoenicke, John Sbarbaro, Catharine Griskowitz, Alexandra Minasian, Cheshta Prasad, Andrew Lewis, Ravi V. Shah, Rajeev Malhotra, Gregory D. Lewis

Institutions: Harvard University, Massachusetts General Hospital, Vanderbilt University

Language: English

Topic: Heart Failure Treatment and Management

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,520

Funders: Sarnoff Cardiovascular Research Foundation, National Institutes of Health, National Heart, Lung, and Blood Institute

Awards: Characterization of Molecular and Physiologic Signatures of Impaired Multi-Organ System Reserve Capacity During Exercise in Heart Failure with Preserved Ejection Fraction, Characterization of Functional Iron Deficiency and Repletion in Heart Failure with Preserved Ejection Fraction

OpenAlex ID: W4390611016

FWCI: 2.223

Cites: 8

Cited by: 8

Related to: 10