Work

Organ-on-chip technology: Opportunities and challenges

Year: 2024

Type: article

Abstract: Organ-on-chip (OOC) technology is an innovative approach that reproduces human organ structures and functions on microfluidic platforms, offering detailed insights into intricate physiological processes. This technology provides unique advantages over conventional in vitro and in vivo models and thus has the potential to become the new standard for biomedical research and drug screening. In this mini-review, we compare OOCs with conventional models, highlighting their differences, and present several applications of OOCs in biomedical research. Additionally, we highlight advancements in OOC technology, particularly in developing multiorgan systems, and discuss the challenges and future directions of this field.

Source: Biotechnology Notes

DOI: 10.1016/j.biotno.2024.01.001

Authors: Santosh Kumar Srivastava, Guo Wei Foo, Nikhil Aggarwal, Matthew Wook Chang

Institution: National University of Singapore

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $700

Funder: U.S. Air Force