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FIGURE 3 from Analysis of Changes in Plasma Cytokine Levels in Response to IL12 Therapy in Three Clinical Trials

Year: 2024

Type: other

Abstract: Cytokine fluxes according to patient response group. Changes in each cytokine level (pg/mL) following IL12 therapy were calculated compared with baseline. These changes were then compared between patients with PD and patients experiencing CB. CB is defined as SD, PR, or CR. ANOVA was employed to test differences in cytokine flux between patient response groups. Cytokines shown here were found to have significantly increased changes in PD patients compared with clinically benefitting patients following IL12 therapy. ANOVA, *, P < 0.05.

DOI: 10.1158/2767-9764.24974987.v1

Authors: Emily Schwarz, Brooke Benner, Lianbo Yu, Fode Tounkara, William E. Carson

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4390703975

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