Deferoxamine Intradermal Delivery Patch for Treatment of a Beta-Thalassemia Wound
Year: 2024
Type: article
Study design: Case Report
Abstract: MINI-ABSTRACT: In this study, we present the first-in-human use of topical deferoxamine (DFO) in the treatment of a beta-thalassemia wound. We elected to use DFO on a patient that suffered from a chronic nonhealing wound in the setting of beta-thalassemia. Despite approximately 55 weeks of marginal improvement in healing, this patient's wound healed completely after 21 weeks of treatment with DFO. We believe that DFO has the potential to accelerate healing in beta-thalassemia wounds through iron chelation.
Source: Annals of Surgery Open
Institutions: Stanford Medicine, Stanford University, University of Arizona
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,000
OpenAlex ID: W4390739672