Modeling and measurement of a miniature piezoelectric ceramic tube fiber scanner for two-photon endomicroscopy
Year: 2024
Type: article
Abstract: To enable optical biopsy in clinical applications, it is essential to miniaturize fiber-optic two-photon endomicroscopy (TPEM). This study used theoretical modeling and experimental measurements on a 1-mm-outer-diameter piezoelectric ceramic tube (PZT) fiber scanner for TPEM. After determining resonant modes, the effects of the driving voltage, PZT length, PZT inner diameter, fiber cantilever length, and fiber eccentricity on the fiber’s first- and second-order resonant characteristics were investigated. A 2.7-mm endomicroscopic probe was also integrated, and its two-photon imaging capability was validated using ex-vivo mouse heart and brain tissues. This study’s findings contribute to the advancement of compact nonlinear endomicroscopy.
Source: Journal of Optical Microsystems
Authors: Conghao Wang, Huilan Liu, Junjie Wang, Qiang Fu, Yanhui Hu, Yuqian Gao, Xinlei Luo, Aimin Wang, Lishuang Feng
Institutions: Beihang University, Peking University, Transcend Vivoscope (China)
Language: English
Subfield: Biophysics
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4390840646