Indian clinical practice consensus guidelines for the management of hypopharyngeal cancer: Update 2022
Year: 2024
Type: article
Abstract: In early hypopharyngeal cancer, definitive radiotherapy (RT) is the preferred modality of treatment. The surgical treatment options are transoral laser microsurgery with selective neck dissection or a partial laryngopharyngectomy plus neck dissection. In locally advanced disease, concurrent chemoradiotherapy (CTRT) is the treatment of choice. Neoadjuvant chemotherapy (NACT) is also a recommended treatment option followed by radical RT/CTRT or surgery followed by adjuvant RT/CTRT, depending on the response. Some patients with locally advanced disease may require total or near total laryngectomy/total or partial pharyngectomy with appropriate neck dissection. Adding targeted therapies like nimotuzumab to cisplatin-based CTRT in locally advanced head-and-neck squamous cell carcinoma improves progression-free survival, locoregional control, and disease-free survival without negatively impacting the quality of life.
Authors: K Govind Babu, Kumar Prabhash, Pankaj Chaturvedi, Moni Kuriakose, Praveen Birur, Anil K. Anand, Ashish Kaushal, Abhishek Mahajan, Judita Syiemlieh, Manish Singhal, Munish Gairola, Prakash Ramachandra, Sumit Goyal, Subashini John, Rohit Nayyar, Vijay M. Patil, Vishal Rao, Vanita Noronha, Vikas Roshan, G. K. Rath
Institutions: HCG Cancer Hospital, Healthcare Global Enterprises, Tata Memorial Hospital, Mazumdar Shaw Medical Centre, Fortis Memorial Research Institute, Clatterbridge Cancer Centre NHS Foundation Trust, Indraprastha Apollo Hospitals, Rajiv Gandhi Cancer Institute and Research Centre, Sri Shankara Cancer Hospital and Research Center, Christian Medical College, Vellore, Max Super Speciality Hospital, P. D. Hinduja Hospital and Medical Research Centre, All India Institute of Medical Sciences
Language: English
Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4390919857