Indian clinical practice consensus guidelines for the management of oropharyngeal cancer: Update 2022
Year: 2024
Type: article
Abstract: The aim of oropharyngeal cancer treatment should be to treat the disease while preserving speech and swallowing abilities. Early-stage disease is generally treated with surgery/radiotherapy (RT). A combination of chemotherapy and RT should be considered instead of RT alone for patients with locally advanced disease. Patients with locally advanced resectable disease can be treated with transoral or open resection of the primary + ipsilateral/bilateral neck dissection ± adjuvant chemoradiotherapy (CTRT)/adjuvant RT. In unresectable locally advanced disease, sequential induction chemotherapy (TPF [docetaxel, cisplatin, fluorouracil]) followed by locoregional treatment with RT or CTRT can be considered. Adding targeted therapies like nimotuzumab to cisplatin-based CTRT in locally advanced head-and-neck squamous cell carcinoma improves the progression-free survival, locoregional control, and disease-free survival without negatively impacting the quality of life.
Authors: Vanita Noronha, Kumar Prabhash, K Govind Babu, Pankaj Chaturvedi, Moni Kuriakose, Praveen Birur, Anil K Anand, Ashish Kaushal, Abhishek Mahajan, Judita Syiemlieh, Manish Singhal, Munish Gairola, Prakash Ramachandra, Sumit Goyal, Subashini John, Rohit Nayyar, Vijay M Patil, Vishal Rao, Vikas Roshan, G.K. Rath
Institutions: Tata Memorial Hospital, HCG Cancer Hospital, Healthcare Global Enterprises, Mazumdar Shaw Medical Centre, Fortis Memorial Research Institute, Clatterbridge Cancer Centre NHS Foundation Trust, Indraprastha Apollo Hospitals, Rajiv Gandhi Cancer Institute and Research Centre, Sri Shankara Cancer Hospital and Research Center, Christian Medical College, Vellore, Max Super Speciality Hospital, P. D. Hinduja Hospital and Medical Research Centre, All India Institute of Medical Sciences
Language: English
Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4390919897