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Case of the Month from the Peter MacCallum Cancer Centre, Melbourne, Australia: an operative approach to large renal angiomyolipoma associated with lymphangioleiomyomatosis

Year: 2024

Type: article

Abstract: A 25-year-old woman was referred to our quaternary cancer centre with a 30-cm left-sided angiomyolipoma (AML), complicated by a bleed into the lesion.CT of the chest revealed small lesions consistent with lymphangioleiomyomatosis.eGFR and haemoglobin on admission was 90 (normal >90 ml/min/1.73m 2 ) and 98 (normal 115-165 g/L), respectively.An interventional radiolist selectively embolized the arterial branches supplying the AML.An elective, open transperitoneal partial nephrectomy was performed 6 weeks later.The AML measured 30 cm with a small 3 9 3 cm area of normal renal parenchymal margin.Histopathology indicated a benign kidney lesion with a postoperative GFR of 90 (normal >90 ml/min/1.73m 2 ).The patient was discharged on Day 5 with follow-up by the adolescent and young adult cancer services.Given the uncommon presentation of large AMLs, this case offers insight into kidney-preserving partial nephrectomy, with initial control guided by an interventional approach.

Source: British Journal of Urology

DOI: 10.1111/bju.16281