Year: 2024
Type: erratum
Abstract: After publication of the article, some readers reached out to JEM to raise concerns about Figs. 5 and 6, specifically regarding the clustering of human mast cells.They highlighted that the analysis did not correct for the influence of donors' gender and/or sequencing technique on the conclusions.At JEM's request, the authors reanalyzed the data to correct for such bias and identified six different mast cell clusters/states with distinct transcriptomic signatures across twelve organs in humans (the previous analysis had identified seven mast cell clusters/states).Accordingly, the clustering of human mast cells and associated mast cell signatures have been revised in the text, in Figs. 5 and 6, and in Tables S3-S5.The conclusions regarding the heterogeneity and diversity of human mast cells remain unchanged.The corrected Figs. 5 and 6 are shown here, as well as changes to the text and figure legends (indicated in bold).Tables S3-S5 have been replaced online.The errors appear in print and PDFs downloaded before January 17, 2024.
Authors: Marie Tauber, Lilian Basso, Jeremy Martin, Luciana Bostan, Marlene Magalhaes Pinto, Guilhem R. Thierry, Raïssa Houmadi, Nadine Serhan, Alexia Loste, Camille Blériot, Jasper B.J. Kamphuis, Mirjana Grujic, Lena Kjellén, Gunnar Pejler, Carle Paul, Xinzhong Dong, Stephen J. Galli, Laurent L. Reber, Florent Ginhoux, Marc Bajenoff, Rebecca Gentek, Nicolas Gaudenzio
Institution: Rockefeller University
Language: English
Topic: Mast cells and histamine
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4391168518