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Impact of climate change on atopic dermatitis: A review by the International Eczema Council

Year: 2024
Type: review
Study design: Systematic Review
Abstract: Atopic dermatitis (AD), the most burdensome skin condition worldwide, is influenced by climatic factors and air pollution; however, the impact of increasing climatic hazards on AD remains poorly characterized. Leveraging an existing framework for 10 climatic hazards related to greenhouse gas emissions, we identified 18 studies with evidence for an impact on AD through a systematic search. Most climatic hazards had evidence for aggravation of AD the impact ranged from direct effects like particulate matter-induced AD exacerbations from wildfires to the potential for indirect effects like drought-induced food insecurity and migration. We then created maps comparing the past, present, and future projected burden of climatic hazards to global AD prevalence data. Data are lacking, especially from those regions most likely to experience more climatic hazards. We highlight gaps important for future research: understanding the synergistic impacts of climatic hazards on AD, long-term disease activity, the differential impact on vulnerable populations, and how basic mechanisms explain population-level trends.
Source: Allergy
DOI: 10.1111/all.16007
Authors: Sheng‐Pei Wang, Nicholas Stefanovic, Raquel L. Orfali, Valeria Aoki, Sara J. Brown, Sandipan Dhar, Lawrence F. Eichenfield, Carsten Flohr, Alex Ha, Camilo Mora, Jenny E. Murase, Misha Rosenbach, Sahana M. Srinivas, Jacob P. Thyssen, Maria L. Wei, Alan D. Irvine, Katrina Abuabara
Institutions: University of California, San Francisco, Trinity College Dublin, Universidade de São Paulo, Institute of Genetics and Cancer, University of Edinburgh, Institute of Child Health, University of California San Diego, King's College London, Guy's and St Thomas' NHS Foundation Trust, University of Hawaiʻi at Mānoa, Palo Alto Medical Foundation, University of Pennsylvania, Indira Gandhi Institute of Child Health, University of Copenhagen, Bispebjerg Hospital, San Francisco VA Medical Center, San Francisco VA Health Care System
Language: English
Open Access status: hybrid
Estimated APC paid: $5,150
Funders: U.S. Department of Defense, U.S. Department of Veterans Affairs, Bristol-Myers Squibb, Pfizer, Sanofi, Regeneron Pharmaceuticals, Incyte, Lundbeckfonden, H. Lundbeck A/S, LEO Pharma
OpenAlex ID: W4391173877
FWCI: 2.196
Cites: 89
Cited by: 51
Related to: 10