Work

De novo synthesis of inherently chiral heteracalix[4]aromatics from enantioselective macrocyclization enabled by chiral phosphoric acid-catalyzed intramolecular S N Ar reaction

Year: 2024

Type: article

Abstract: ,O-calix[2]arene[2]triazines from enantioselective macrocyclization enabled by chiral phosphoric acid-catalyzed intramolecular nucleophilic aromatic substitution reaction. In contrast to documented examples, the inherent chirality of the acquired compounds arises from one heteroatom difference in the linking positions of heteracalix[4](het)arenes.

Source: Chemical Science

DOI: 10.1039/d3sc06436k

Authors: Xing-Chi Li, Ying Cheng, Xu-Dong Wang, Shuo Tong, Mei-Xiang Wang

Institutions: Chinese Academy of Sciences, Beijing Normal University, Institute of Chemistry, Tsinghua University

Language: English

Topic: Supramolecular Chemistry and Complexes

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: National Natural Science Foundation of China, Tsinghua University

Awards: G1698011894, G2376201943, G5312132887, G5849804789