Work

FIGURE 4 from A Revised Molecular Model of Ovarian Cancer Biomarker CA125 (MUC16) Enabled by Long-read Sequencing

Year: 2024

Type: other

Abstract: Schematic models of MUC16. Top, The model derived from the sequence determined by O'Brien and colleagues (2001) containing 63 units in the tandem repeat domain. Bottom, The model proposed in this study, containing 19 units in the tandem repeat domain. The repeats that are not included in the proposed model (6, 10, and 12 through 53) are shown as white circles. Ellipses represent repeats that are not shown for clarity. The N-terminal domain is much larger than shown here and is also compressed for clarity.

DOI: 10.1158/2767-9764.25118638.v1

Authors: Chien-Wei Wang, Simon D. Weaver, Nicha Boonpattrawong, Naviya Schuster-Little, Manish Patankar, Rebecca J. Whelan

Language: English

Topic: Glycosylation and Glycoproteins Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4391386247

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